Publication: Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont
Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont
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Hsiao, C.-C., Sieber, S., Georgiou, A., Bailly, A., Emmanouilidou, D., Carlier, A., Eberl, L., & Gademann, K. (2019). Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont. Chemistry, 25(7), 1722–1726. https://doi.org/10.1002/chem.201805693
Abstract
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Abstract
The plant Psychotria kirkii hosts an obligatory bacterial symbiont, Candidatus Burkholderia kirkii, in nodules on their leaves. Recently, a glucosylated derivative of (+)-streptol, (+)-streptol glucoside, was isolated from the nodulated leaves and was found to possess a plant growth inhibitory activity. To establish a structure-activity relationship study, a convergent strategy was developed to obtain several pseudosugars from a single synthetic precursor. Furthermore, the glucosylation of streptol was investigated in detail and condi
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Creators (Authors)
- Hsiao, Chien-Chi
- Georgiou, Antri
- Bailly, Aurélien
- Emmanouilidou, Despina
- Carlier, Aurélien
- Eberl, Leo
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Citations
Hsiao, C.-C., Sieber, S., Georgiou, A., Bailly, A., Emmanouilidou, D., Carlier, A., Eberl, L., & Gademann, K. (2019). Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont. Chemistry, 25(7), 1722–1726. https://doi.org/10.1002/chem.201805693
