Publication: Effect of denosumab on peripheral compartmental bone density, microarchitecture and estimated bone strength in de novo kidney transplant recipients
Effect of denosumab on peripheral compartmental bone density, microarchitecture and estimated bone strength in de novo kidney transplant recipients
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Bonani, M., Meyer, U., Frey, D., Graf, N., Bischoff-Ferrari, H. A., & Wüthrich, R. P. (2016). Effect of denosumab on peripheral compartmental bone density, microarchitecture and estimated bone strength in de novo kidney transplant recipients. Kidney & Blood Pressure Research, 41(5), 614–622. https://doi.org/10.1159/000447930
Abstract
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BACKGROUND/AIMS: In a randomized controlled clinical trial in kidney transplant recipients (NCT01377467) we have recently shown that RANKL inhibition with denosumab significantly improved areal bone mineral density (aBMD) when given during the first year after transplantation. The effect of denosumab on skeletal microstructure and bone strength in kidney transplant recipients is not known. METHODS: The purpose of the present bone microarchitecture ancillary study was to investigate high-resolution peripheral quantitative computed tomo
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- Bonani, Marco
- Meyer, Ursina
- Frey, Diana
- Graf, Nicole
- Bischoff-Ferrari, Heike A
- Wüthrich, Rudolf P
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Citations
Bonani, M., Meyer, U., Frey, D., Graf, N., Bischoff-Ferrari, H. A., & Wüthrich, R. P. (2016). Effect of denosumab on peripheral compartmental bone density, microarchitecture and estimated bone strength in de novo kidney transplant recipients. Kidney & Blood Pressure Research, 41(5), 614–622. https://doi.org/10.1159/000447930
