Publication: Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica
Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica
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Schneider, P., Krucker, T., Meyer, E., Ulmann-Schuler, A., Weber, B., Stampanoni, M., & Müller, R. (2009). Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica. Microscopy Research and Technique, 72(9), 690–701. https://doi.org/10.1002/jemt.20720
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Recent evidence suggests a close functional relationship between osteogenesis and angiogenesis as well as between bone remodeling and bone vascularization. Consequently, there is a need for visual inspection and quantitative analysis of the bone vasculature. We therefore adapted and implemented two different vascular corrosion casting (VCC) protocols using a polyurethane-based casting resin in mice for a true three-dimensional (3D), direct, and simultaneous measurement of bone tissue and vascular morphology by micro-computed tomograph
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Schneider, P., Krucker, T., Meyer, E., Ulmann-Schuler, A., Weber, B., Stampanoni, M., & Müller, R. (2009). Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica. Microscopy Research and Technique, 72(9), 690–701. https://doi.org/10.1002/jemt.20720