Publication: Dynamics of virus shedding and in situ confirmation of Chelonid Herpesvirus 5 in Hawaiian Green Turtles with fibropapillomatosis
Dynamics of virus shedding and in situ confirmation of Chelonid Herpesvirus 5 in Hawaiian Green Turtles with fibropapillomatosis
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Work, T. M., Dagenais, J., Balazs, G. H., Schetle, N., & Ackermann, M. (2015). Dynamics of virus shedding and in situ confirmation of Chelonid Herpesvirus 5 in Hawaiian Green Turtles with fibropapillomatosis. Veterinary Pathology, 52(6), 1195–1201. https://doi.org/10.1177/0300985814560236
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Cancers in humans and animals can be caused by viruses, but virus-induced tumors are considered to be poor sites for replication of intact virions (lytic replication). Fibropapillomatosis (FP) is a neoplastic disease associated with a herpesvirus, chelonid herpesvirus 5 (ChHV5), that affects green turtles globally. ChHV5 probably replicates in epidermal cells of tumors, because epidermal intranuclear inclusions (EIIs) contain herpesvirus-like particles. However, although EIIs are a sign of herpesvirus replication, they have not yet be
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Work, T. M., Dagenais, J., Balazs, G. H., Schetle, N., & Ackermann, M. (2015). Dynamics of virus shedding and in situ confirmation of Chelonid Herpesvirus 5 in Hawaiian Green Turtles with fibropapillomatosis. Veterinary Pathology, 52(6), 1195–1201. https://doi.org/10.1177/0300985814560236