Publication: CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches
CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches
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Werling, A. M., Bobrowski, E., Taurines, R., Gundelfinger, R., Romanos, M., Grünblatt, E., & Walitza, S. (2016). CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches. Journal of Neural Transmission, 123(3), 353–363. https://doi.org/10.1007/s00702-015-1458-5
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The Contactin Associated Protein-like 2 (CNTNAP2) gene has been discussed to be associated with different symptoms of autism spectrum disorders (ASDs) and other neurodevelopmental disorders. We aimed to elucidate the genetic association of CNTNAP2 within high functioning ASD (HFA), focusing on autism specific symptoms and reducing intelligence related factors. Furthermore, we compared our findings conducting a meta-analysis in patients with ASD and HFA only. A case-control association study was performed for HFA (HFA, n = 105; control
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Werling, A. M., Bobrowski, E., Taurines, R., Gundelfinger, R., Romanos, M., Grünblatt, E., & Walitza, S. (2016). CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches. Journal of Neural Transmission, 123(3), 353–363. https://doi.org/10.1007/s00702-015-1458-5