Publication: Gammaherpesvirus-Induced T Cell-Mediated Immune Control and Tumorigenesis in a Model of Dual-Infection
Gammaherpesvirus-Induced T Cell-Mediated Immune Control and Tumorigenesis in a Model of Dual-Infection
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Rieble, L. (2024). Gammaherpesvirus-Induced T Cell-Mediated Immune Control and Tumorigenesis in a Model of Dual-Infection. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258777
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Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are two humanotropic g-herpesviruses that infect a large part of the human population. They can both persist lifelong in human B cells and contribute to a number of B cell lymphoproliferative diseases, that mostly arise in immunocompromised individuals.
Primary effusion lymphoma (PEL) is associated with KSHV, but about 90% of tumors are also positive for EBV. The first part of this PhD thesis is a review that sums up the knowledge on EBV and KSHV in PEL and inn
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Rieble, L. (2024). Gammaherpesvirus-Induced T Cell-Mediated Immune Control and Tumorigenesis in a Model of Dual-Infection. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258777