Publication: Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men
Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men
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Daryadel, A., Bettoni, C., Haider, T., Imenez Silva, P. H., Schnitzbauer, U., Pastor-Arroyo, E. M., Wenger, R. H., Gassmann, M., & Wagner, C. A. (2018). Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men. Pflügers Archiv : European Journal of Physiology, 470, 1569–1582. https://doi.org/10.1007/s00424-018-2171-7
Abstract
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Fibroblast growth factor 23 (FGF23) is a major endocrine regulator of phosphate and 1,25 (OH)2 vitamin D3 metabolism and is mainly produced by osteocytes. Its production is upregulated by a variety of factors including 1,25 (OH)2 vitamin D3, high dietary phosphate intake, and parathyroid hormone (PTH). Recently, iron deficiency and hypoxia have been suggested as additional regulators of FGF23 and a role of erythropoietin (EPO) was shown. However, the regulation of FGF23 by EPO and the impact on phosphate and 1,25(OH)2 vitamin D3 are n
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- Daryadel, Arezoo
- Bettoni, Carla
- Haider, Thomas
- Imenez Silva, Pedro H
- Schnitzbauer, Udo
- Pastor-Arroyo, Eva Maria
- Wenger, Roland H
- Gassmann, Max
- Wagner, Carsten A
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Daryadel, A., Bettoni, C., Haider, T., Imenez Silva, P. H., Schnitzbauer, U., Pastor-Arroyo, E. M., Wenger, R. H., Gassmann, M., & Wagner, C. A. (2018). Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men. Pflügers Archiv : European Journal of Physiology, 470, 1569–1582. https://doi.org/10.1007/s00424-018-2171-7
