Publication: Severe signs of hyponatremia secondary to desmopressin treatment for enuresis: a systematic review
Severe signs of hyponatremia secondary to desmopressin treatment for enuresis: a systematic review
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Lucchini, B., Simonetti, G. D., Ceschi, A., Lava, S. A. G., Faré, P. B., & Bianchetti, M. G. (2013). Severe signs of hyponatremia secondary to desmopressin treatment for enuresis: a systematic review. Journal of Pediatric Urology, 9, 1049–1053. https://doi.org/10.1016/j.jpurol.2013.02.012
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OBJECTIVE: Dilutional hyponatremia is a serious adverse effect of desmopressin, a vasopressin analog that is widely prescribed to manage monosymptomatic enuresis. The presentation of hyponatremia, largely related to cerebral dysfunction, can include severe signs like altered mental status and seizures. METHODS: We reviewed the literature dealing with altered mental status or seizures in enuretic subjects on desmopressin. The retained publications included patients who were described individually, revealing data on mode of administrati
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Lucchini, B., Simonetti, G. D., Ceschi, A., Lava, S. A. G., Faré, P. B., & Bianchetti, M. G. (2013). Severe signs of hyponatremia secondary to desmopressin treatment for enuresis: a systematic review. Journal of Pediatric Urology, 9, 1049–1053. https://doi.org/10.1016/j.jpurol.2013.02.012