Assessment of extracranial metastatic disease in patients with brain metastases: How much effort is needed in the context of evolving survival prediction models?

Nieder, Carsten; Mehta, Minesh P; Guckenberger, Matthias; Gaspar, Laurie E; Rusthoven, Chad G; Sahgal, Arjun; Grosu, Anca L; De Ruysscher, Dirk

doi:10.1016/j.radonc.2021.02.038

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Nieder, C., Mehta, M. P., Guckenberger, M., Gaspar, L. E., Rusthoven, C. G., Sahgal, A., Grosu, A. L., & De Ruysscher, D. (2021). Assessment of extracranial metastatic disease in patients with brain metastases: How much effort is needed in the context of evolving survival prediction models? Radiotherapy and Oncology, 159, 17–20. https://doi.org/10.1016/j.radonc.2021.02.038

Abstract

Survival prediction models may serve as decision-support tools for clinicians who have to assign the right treatment to each patient, in a manner whereby harmful over- or undertreatment is avoided as much as possible. Current models differ regarding their components, the overall number of components and the weighting of individual components. Some of the components are easy to assess, such as age or primary tumor type. Others carry the risk of inter-assessor inconsistency and time-dependent variation. The present publication focuses o