Publication: Generation of integration-free induced pluripotent stem cells from healthy individuals
Generation of integration-free induced pluripotent stem cells from healthy individuals
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Yde Ohki, C. M., Grossmann, L., Döring, C., Hoffmann, P., Herms, S., Werling, A. M., Walitza, S., & Grünblatt, E. (2021). Generation of integration-free induced pluripotent stem cells from healthy individuals. Stem Cell Research, 53, 102269. https://doi.org/10.1016/j.scr.2021.102269
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Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6-18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.
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Yde Ohki, C. M., Grossmann, L., Döring, C., Hoffmann, P., Herms, S., Werling, A. M., Walitza, S., & Grünblatt, E. (2021). Generation of integration-free induced pluripotent stem cells from healthy individuals. Stem Cell Research, 53, 102269. https://doi.org/10.1016/j.scr.2021.102269