Publication:

Predicting Adverse Radiation Effects in Brain Tumors After Stereotactic Radiotherapy With Deep Learning and Handcrafted Radiomics

Date

Date

Date
2022
Journal Article
Published version

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Keek, S. A., Beuque, M., Primakov, S., Woodruff, H. C., Chatterjee, A., van Timmeren, J. E., Vallières, M., Hendriks, L. E. L., Kraft, J., Andratschke, N., Braunstein, S. E., Morin, O., & Lambin, P. (2022). Predicting Adverse Radiation Effects in Brain Tumors After Stereotactic Radiotherapy With Deep Learning and Handcrafted Radiomics. Frontiers in Oncology, 12, 920393. https://doi.org/10.3389/fonc.2022.920393

Abstract

Abstract

Abstract

Introduction

There is a cumulative risk of 20-40% of developing brain metastases (BM) in solid cancers. Stereotactic radiotherapy (SRT) enables the application of high focal doses of radiation to a volume and is often used for BM treatment. However, SRT can cause adverse radiation effects (ARE), such as radiation necrosis, which sometimes cause irreversible damage to the brain. It is therefore of clinical interest to identify patients at a high risk of developing ARE. We hypothesized that models trained with radiomics features, deep

Additional indexing

Creators (Authors)

  • Keek, Simon A
    affiliation.icon.alt
  • Beuque, Manon
    affiliation.icon.alt
  • Primakov, Sergey
    affiliation.icon.alt
  • Woodruff, Henry C
    affiliation.icon.alt
  • Chatterjee, Avishek
    affiliation.icon.alt
  • van Timmeren, Janita E
    affiliation.icon.alt
  • Vallières, Martin
    affiliation.icon.alt
  • Hendriks, Lizza E L
    affiliation.icon.alt
  • Kraft, Johannes
    affiliation.icon.alt
  • Andratschke, Nicolaus
    affiliation.icon.alt
  • Braunstein, Steve E
    affiliation.icon.alt
  • Morin, Olivier
    affiliation.icon.alt
  • Lambin, Philippe
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
12

Page range/Item number

Page range/Item number

Page range/Item number
920393

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2022

Date available

Date available

Date available
2022-10-03

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2234-943X

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Keek, S. A., Beuque, M., Primakov, S., Woodruff, H. C., Chatterjee, A., van Timmeren, J. E., Vallières, M., Hendriks, L. E. L., Kraft, J., Andratschke, N., Braunstein, S. E., Morin, O., & Lambin, P. (2022). Predicting Adverse Radiation Effects in Brain Tumors After Stereotactic Radiotherapy With Deep Learning and Handcrafted Radiomics. Frontiers in Oncology, 12, 920393. https://doi.org/10.3389/fonc.2022.920393

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