Publication: Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy
Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy
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Savarino, E., Tutuian, R., Zentilin, P., Dulbecco, P., Pohl, D., Marabotto, E., Parodi, A., Sammito, G., Gemignani, L., Bodini, G., & Savarino, V. (2010). Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy. American Journal of Gastroenterology, 105(5), 1053–1061. https://doi.org/10.1038/ajg.2009.670
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OBJECTIVES: We sought to compare reflux and symptom association patterns in patients with nonerosive reflux disease (NERD), erosive esophagitis (EE), and in healthy volunteers (HVs).
METHODS: Patients with EE and NERD underwent combined impedance-pH monitoring. Normal values were defined on the basis of previously collected data from 48 HVs. We evaluated distal esophageal acid exposure time (AET), number and type of reflux episodes (acid, nonacid), acid and bolus clearance times, proximal extension of reflux episodes, and symptom ass
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Savarino, E., Tutuian, R., Zentilin, P., Dulbecco, P., Pohl, D., Marabotto, E., Parodi, A., Sammito, G., Gemignani, L., Bodini, G., & Savarino, V. (2010). Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy. American Journal of Gastroenterology, 105(5), 1053–1061. https://doi.org/10.1038/ajg.2009.670