Publication: Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice.
Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice.
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Steinbach, J. P., Weissenberger, J., & Aguzzi, A. (1999). Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice. Neuropathology and Applied Neurobiology, 25(6), 468–480. https://doi.org/10.1046/j.1365-2990.1999.00206.x
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Abstract
To characterize the development of tissue damage following cryogenic injury to the mouse cortex, the time course of histopathological changes, transcriptional responses and DNA strand breaks following application of a liquid nitrogen-cooled probe to the surface of the parietal bone were assessed. Distinct phases of tissue damage were observed: after 30 min, there was demarcation of a core lesion followed by mainly necrotic cell death starting 2 h after injury. At 12 hours, progressive apoptotic death of scattered cells in the peripher
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- Steinbach, J P
- Weissenberger, J
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Steinbach, J. P., Weissenberger, J., & Aguzzi, A. (1999). Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice. Neuropathology and Applied Neurobiology, 25(6), 468–480. https://doi.org/10.1046/j.1365-2990.1999.00206.x