Publication: The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells
The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells
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Oesch, F., Arand, M., Coughtrie, M. W., Burchell, B., & Steinberg, P. (1992). The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells. Biochemical Pharmacology, 43, 731–737. https://doi.org/10.1016/0006-2952(92)90237-D
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Abstract
Activities for the glucuronidation of 1-naphthol, morphine and bilirubin as well as for the sulfation of 2-naphthol have been determined in homogenates of parenchymal, Kupffer and endothelial cells isolated from livers of untreated and Aroclor 1254-pretreated rats. In addition, Western blot analyses using different polyclonal antibodies against UDP-glucuronosyltransferases (UDP-GTs) were performed with similar preparations. All enzymes under investigation were expressed at high levels in liver parenchymal cells. The constitutive expre
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- Oesch, F
- Coughtrie, M W
- Burchell, B
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Oesch, F., Arand, M., Coughtrie, M. W., Burchell, B., & Steinberg, P. (1992). The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells. Biochemical Pharmacology, 43, 731–737. https://doi.org/10.1016/0006-2952(92)90237-D
