Atrial natriuretic peptide and cardiac troponin I concentrations in healthy Warmblood horses and in Warmblood horses with mitral regurgitation at rest and after exercise

Trachsel, Dagmar S; Schwarzwald, Colin C; Bitschnau, Caroline; Grenacher, Beat; Weishaupt, Michael A

doi:10.1016/j.jvc.2012.12.003

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Trachsel, D. S., Schwarzwald, C. C., Bitschnau, C., Grenacher, B., & Weishaupt, M. A. (2013). Atrial natriuretic peptide and cardiac troponin I concentrations in healthy Warmblood horses and in Warmblood horses with mitral regurgitation at rest and after exercise. Journal of Veterinary Cardiology, 15(2), 105–121. https://doi.org/10.1016/j.jvc.2012.12.003

Abstract

OBJECTIVE: Atrial natriuretic peptide (ANP) and cardiac troponin I (cTnI) serve as biomarkers for increased cardiac pressure/volume loading and for myocardial stress or damage. The objective was to describe the time course of plasma ANP concentrations (CpANP) and plasma cTnI concentrations (CpcTnI) in horses with mitral regurgitation (MR) compared to healthy horses at rest and after exercise, and to describe the relationship of CpANP with cardiac dimensions and intracardiac pressures. ANIMALS: 15 healthy Warmblood horses and 7 Warmblo