Publication: Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo
Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo
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Baumann, J., Tsao, C.-C., Patkar, S., Huang, S.-F., Francia, S., Magnussen, S. N., Gassmann, M., Vogel, J., Köster-Hegmann, C., & Ogunshola, O. O. (2022). Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo. Fluids and Barriers of the CNS, 19, 6. https://doi.org/10.1186/s12987-021-00302-y
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Background: Ways to prevent disease-induced vascular modifications that accelerate brain damage remain largely elusive. Improved understanding of perivascular cell signalling could provide unparalleled insight as these cells impact vascular stability and functionality of the neurovascular unit as a whole. Identifying key drivers of astrocyte and pericyte responses that modify cell–cell interactions and crosstalk during injury is key. At the cellular level, injury-induced outcomes are closely entwined with activation of the hypoxia-ind
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- Baumann, Julia
- Tsao, Chih-Chieh
- Patkar, Shalmali
- Huang, Sheng-Fu
- Francia, Simona
- Magnussen, Synnøve Norvoll
- Gassmann, Max
- Vogel, Johannes
- Köster-Hegmann, Christina
- Ogunshola, Omolara O
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Baumann, J., Tsao, C.-C., Patkar, S., Huang, S.-F., Francia, S., Magnussen, S. N., Gassmann, M., Vogel, J., Köster-Hegmann, C., & Ogunshola, O. O. (2022). Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo. Fluids and Barriers of the CNS, 19, 6. https://doi.org/10.1186/s12987-021-00302-y
