Publication: Revised time scales of RNA virus evolution based on spatial information
Revised time scales of RNA virus evolution based on spatial information
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Saxenhofer, M., Weber de Melo, V., Ulrich, R. G., & Heckel, G. (2017). Revised time scales of RNA virus evolution based on spatial information. Proceedings of the Royal Society of London, Series B: Biological Sciences, 284(1860), 20170857. https://doi.org/10.1098/rspb.2017.0857
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The time scales of pathogen evolution are of major concern in the context of public and veterinary health, epidemiology and evolutionary biology. Dating the emergence of a pathogen often relies on estimates of evolutionary rates derived from nucleotide sequence data. For many viruses, this has yielded estimates of evolutionary origins only a few hundred years in the past. Here we demonstrate through the incorporation of geographical information from virus sampling that evolutionary age estimates of two European hantaviruses are severe
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Saxenhofer, M., Weber de Melo, V., Ulrich, R. G., & Heckel, G. (2017). Revised time scales of RNA virus evolution based on spatial information. Proceedings of the Royal Society of London, Series B: Biological Sciences, 284(1860), 20170857. https://doi.org/10.1098/rspb.2017.0857