Publication: The neuropeptide galanin modulates natural killer cell function
The neuropeptide galanin modulates natural killer cell function
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Koller, A., Bianchini, R., Schlager, S., Münz, C., Kofler, B., & Wiesmayr, S. (2017). The neuropeptide galanin modulates natural killer cell function. Neuropeptides, 64, 109–115. https://doi.org/10.1016/j.npep.2016.11.002
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Natural killer (NK) cells are part of the innate immune system and combat pathogens and tumors by secreting pro-inflammatory cytokines like interferon gamma (IFN-γ) and by their cytotoxic action. Galanin is a neuropeptide also expressed in peripheral tissue where it impacts several physiological functions, including inflammation. The effects of galanin are mediated via three receptors, GAL1-3. Since other neuropeptides have been shown to regulate NK cell activity, we investigated the potential of galanin to modulate human NK cell func
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Koller, A., Bianchini, R., Schlager, S., Münz, C., Kofler, B., & Wiesmayr, S. (2017). The neuropeptide galanin modulates natural killer cell function. Neuropeptides, 64, 109–115. https://doi.org/10.1016/j.npep.2016.11.002