Publication: Environmentally relevant concentrations of 17alpha-ethinylestradiol (EE2) interfere with the growth hormone (GH)/insulin-like growth factor (IGF)-I system in developing bony fish
Environmentally relevant concentrations of 17alpha-ethinylestradiol (EE2) interfere with the growth hormone (GH)/insulin-like growth factor (IGF)-I system in developing bony fish
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Shved, N., Berishvili, G., Baroiller, J. F., Segner, H., & Reinecke, M. (2008). Environmentally relevant concentrations of 17alpha-ethinylestradiol (EE2) interfere with the growth hormone (GH)/insulin-like growth factor (IGF)-I system in developing bony fish. Toxicological Sciences, 106(1), 93–102. https://doi.org/10.1093/toxsci/kfn150
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The aim of this study was to evaluate whether effects of environmental estrogens on fish growth and reproduction may be mediated via modulating the growth hormone (GH)/insulin-like growth factor I (IGF-I) system. To this end, developing male and female monosex populations of tilapia were exposed to 17alpha-ethinylestradiol (EE2) at 5 and 25 ng EE2/l water from 10-day postfertilization (DPF) until 100 DPF. Under exposure to both EE2 concentrations, sex ratio shifted toward more females and body length, and weight were significantly red
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- Shved, N
- Berishvili, G
- Baroiller, J F
- Segner, H
- Reinecke, M
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Shved, N., Berishvili, G., Baroiller, J. F., Segner, H., & Reinecke, M. (2008). Environmentally relevant concentrations of 17alpha-ethinylestradiol (EE2) interfere with the growth hormone (GH)/insulin-like growth factor (IGF)-I system in developing bony fish. Toxicological Sciences, 106(1), 93–102. https://doi.org/10.1093/toxsci/kfn150
