Publication: Involvement of nitric oxide in lipopolysaccharide induced anorexia
Involvement of nitric oxide in lipopolysaccharide induced anorexia
Date
Date
Date
Citations
Riediger, T., Cordani, C., Potes, C. S., & Lutz, T. A. (2010). Involvement of nitric oxide in lipopolysaccharide induced anorexia. Pharmacology Biochemistry and Behavior, 97(1), 112–120. https://doi.org/10.1016/j.pbb.2010.04.015
Abstract
Abstract
Abstract
Treatment with the bacterial endotoxin lipopolysaccharide (LPS) is a commonly used model to induce disease-related anorexia. Following LPS treatment inducible nitric oxide synthase (iNOS) is expressed in the hypothalamic arcuate nucleus (ARC), where nitric oxide (NO) inhibits orexigenic neurons. Intracellular STAT signaling is triggered by inflammatory stimuli and has been linked to the transcriptional regulation of iNOS. We evaluated whether pharmacological blockade of iNOS by the specific inhibitor 1400W attenuates LPS-induced anore
Additional indexing
Creators (Authors)
- Riediger, Thomas
- Cordani, C
- Potes, C S
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
Number
Number
Number
Page Range
Page Range
Page Range
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Citations
Riediger, T., Cordani, C., Potes, C. S., & Lutz, T. A. (2010). Involvement of nitric oxide in lipopolysaccharide induced anorexia. Pharmacology Biochemistry and Behavior, 97(1), 112–120. https://doi.org/10.1016/j.pbb.2010.04.015
