Publication: Structural and Functional Characterization of the Mycobacterial Siderophore Exporter MmpL4
Structural and Functional Characterization of the Mycobacterial Siderophore Exporter MmpL4
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Earp, J. (2024). Structural and Functional Characterization of the Mycobacterial Siderophore Exporter MmpL4. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-261300
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Mycobacterium tuberculosis is an obligate human pathogen that causes tuberculosis, a disease resulting in approximately 10 million deaths in 2022, making it the primary cause of death from a single infectious agent. The treatment regime for TB is extensive and involves administration of up to four drugs daily for six months. The emergence of multi-drug resistance to these first-line antibiotics further complicates treatment. Drug resistance mechanisms of M. tuberculosis include modification of pro-drug activating enzymes, modification
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Earp, J. (2024). Structural and Functional Characterization of the Mycobacterial Siderophore Exporter MmpL4. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-261300
