Publication: Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep
Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep
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Flück, M., von Rechenberg, B., Wieser, K., Meyer, D. C., Gerber, C., & et al. (2017). Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep. Journal of Steroid Biochemistry and Molecular Biology, 165, 382–395. https://doi.org/10.1016/j.jsbmb.2016.08.005
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Reversal of fatty infiltration of pennate rotator cuff muscle after tendon release is hitherto impossible. The administration of nandrolone starting at the time of tendon release prevents the increase in fat content, but does not revert established fatty infiltration. We hypothesised that tendon release and myotendinous retraction cause alterations in lipid related gene expression leading to fatty muscle infiltration, which can be suppressed by nandrolone through its genomic actions if applied immediately after tendon release. The eff
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- Flück, Martin
- von Rechenberg, Brigitte
- Wieser, Karl
- Meyer, D C
- Gerber, Christian
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Citations
Flück, M., von Rechenberg, B., Wieser, K., Meyer, D. C., Gerber, C., & et al. (2017). Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep. Journal of Steroid Biochemistry and Molecular Biology, 165, 382–395. https://doi.org/10.1016/j.jsbmb.2016.08.005
