Publication: Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation
Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation
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Kastnerova, L., Luzar, B., Goto, K., Grishakov, V., Gatalica, Z., Kamarachev, J., Martinek, P., Hájková, V., Grossmann, P., Imai, H., Fukui, H., Michal, M., & Kazakov, D. V. (2019). Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation. American Journal of Surgical Pathology, 43(8), 1092–1098. https://doi.org/10.1097/PAS.0000000000001261
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Secretory carcinoma of the skin is a rare adnexal carcinoma, which is morphologically and immunohistochemically identical to secretory carcinoma of the breast and is associated with the presence of t (12;15) translocation, resulting in the ETV6-NTRK3 gene fusion. Nineteen cases of primary cutaneous secretory carcinoma have been previously published in the literature. In this study, we describe 6 new cases of secretory carcinoma of the skin. The study group consisted of 5 female patients and 1 male patient, ranging in age from 57 to 98
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Kastnerova, L., Luzar, B., Goto, K., Grishakov, V., Gatalica, Z., Kamarachev, J., Martinek, P., Hájková, V., Grossmann, P., Imai, H., Fukui, H., Michal, M., & Kazakov, D. V. (2019). Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation. American Journal of Surgical Pathology, 43(8), 1092–1098. https://doi.org/10.1097/PAS.0000000000001261