Publication: Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation
Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation
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Zundler, S., Günther, C., Kremer, A. E., Zaiss, M. M., Rothhammer, V., & Neurath, M. F. (2023). Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nature Reviews. Gastroenterology & Hepatology, 20(1), 50–64. https://doi.org/10.1038/s41575-022-00663-1
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Immune cell trafficking is a complex and tightly regulated process that is indispensable for the body's fight against pathogens. However, it is also increasingly acknowledged that dysregulation of cell trafficking contributes to the pathogenesis of immune-mediated inflammatory diseases (IMIDs) in gastroenterology and hepatology, such as inflammatory bowel disease and primary sclerosing cholangitis. Moreover, altered cell trafficking has also been implicated as a crucial step in the immunopathogenesis of other IMIDs, such as rheumatoid
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Zundler, S., Günther, C., Kremer, A. E., Zaiss, M. M., Rothhammer, V., & Neurath, M. F. (2023). Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nature Reviews. Gastroenterology & Hepatology, 20(1), 50–64. https://doi.org/10.1038/s41575-022-00663-1