Publication: Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial
Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial
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Wess, G., Kresken, J., Wendt, R., Gaugele, J., Killich, M., Keller, L., Simak, J., Holler, P., Bauer, A., Küchenhof, H., & Glaus, T. (2020). Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial. Journal of Veterinary Internal Medicine, 34(6), 2232–2241. https://doi.org/10.1111/jvim.15863
Abstract
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Abstract
Background: Triple therapy (TT) consisting of furosemide, pimobendan, and anangiotensin-converting enzyme inhibitor (ACEI) frequently is recommended for thetreatment of congestive heart failure (CHF) attributable to myxomatous mitral valvedisease (MMVD). However, the effect of adding an ACEI to the combination ofpimobendan and furosemide (dual therapy [DT]) so far has not been evaluatedprospectively. Hypothesis: Triple therapy will extend survival time compared to DT in dogs withCHF secondary to MMVD. Animals: Client-owned dogs presen
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- Wess, Gerhard
- Kresken, Jan‐Gerd
- Wendt, Ralph
- Gaugele, Juliane
- Killich, Markus
- Keller, Lisa
- Simak, Julia
- Holler, Peter
- Bauer, Alexander
- Küchenhof, Helmut
- Glaus, Tony
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Wess, G., Kresken, J., Wendt, R., Gaugele, J., Killich, M., Keller, L., Simak, J., Holler, P., Bauer, A., Küchenhof, H., & Glaus, T. (2020). Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial. Journal of Veterinary Internal Medicine, 34(6), 2232–2241. https://doi.org/10.1111/jvim.15863
