Publication: Shaping of signal transmission at the photoreceptor synapse by EAAT2 glutamate transporters
Date
Date
Date
2017
Journal Article
Published version
Abstract
Abstract
Abstract
Photoreceptor ribbon synapses tonically release glutamate. To ensure efficient signal transmission and prevent glutamate toxicity, a highly efficient glutamate removal system provided by members of the SLC1 gene family is required. By using a combination of biophysical and in vivo studies, we elucidate the role of excitatory amino acid transporter 2 (EAAT2) proteins in synaptic glutamate homeostasis at the zebrafish photoreceptor synapse. The main glutamate sink is provided by the glial EAAT2a, reflected by reduced electroretinographi
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97 since deposited on 2017-08-24
94last week
Acq. date: 2025-11-13
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192 since deposited on 2017-08-24
191last week
Acq. date: 2025-11-13
Additional indexing
Creators (Authors)
- Niklaus, Stephanie
- Cadetti, Lucia
- Vom Berg-Maurer, Colette M
- Lehnherr, André
- Hotz, Adriana L
- Forster, Ian C
- Gesemann, Matthias
Volume
Volume
Volume
4
Number
Number
Number
3
Page range/Item number
Page range/Item number
Page range/Item number
e0339
Item Type
Item Type
Item Type
Journal Article
Language
Language
Language
English
Publication date
Publication date
Publication date
2017-06-05
Date available
Date available
Date available
2017-08-24
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
2373-2822
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Metrics
Downloads
97 since deposited on 2017-08-24
94last week
Acq. date: 2025-11-13
Views
192 since deposited on 2017-08-24
191last week
Acq. date: 2025-11-13
Gold Open Access
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