Publication: The acute autonomic stress response and amniotic fluid glucocorticoids in second-trimester pregnant women
The acute autonomic stress response and amniotic fluid glucocorticoids in second-trimester pregnant women
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La Marca-Ghaemmaghami, P., Dainese, S. M., La Marca, R., Zimmermann, R., & Ehlert, U. (2015). The acute autonomic stress response and amniotic fluid glucocorticoids in second-trimester pregnant women. Psychosomatic Medicine, 77(1), 41–49. https://doi.org/10.1097/PSY.0000000000000130
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OBJECTIVE: The maternal autonomic nervous system (ANS) has received little attention in the investigation of biological mechanisms linking prenatal stress to fetal cortisol (F) excess. In vitro, norepinephrine and epinephrine inhibit placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which protects the fetus from F overexposure by inactivating it to cortisone (E). Here, we investigated the acute ANS stress response to an amniocentesis and its association with amniotic fluid F, E, and E/(E + F) as a marker of fetoplacental 1
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La Marca-Ghaemmaghami, P., Dainese, S. M., La Marca, R., Zimmermann, R., & Ehlert, U. (2015). The acute autonomic stress response and amniotic fluid glucocorticoids in second-trimester pregnant women. Psychosomatic Medicine, 77(1), 41–49. https://doi.org/10.1097/PSY.0000000000000130