Publication:

Neuroserpin is post-transcriptionally regulated by thyroid hormone.

Date

Date

Date
2004
Journal Article
Published version

Citations

Citation copied

Navarro-Yubero, C., Cuadrado, A., Sonderegger, P., & Muñoz, A. (2004). Neuroserpin is post-transcriptionally regulated by thyroid hormone. Molecular Brain Research, 123(1–2), 56–65. https://doi.org/10.1016/j.molbrainres.2003.12.018

Abstract

Abstract

Abstract

Neuroserpin is a serine protease inhibitor expressed in the developing and the adult nervous system. Studies with genetically modified mice indicate a role of neuroserpin in the regulation of anxiety. Mutations in the neuroserpin gene cause protein polymerization and formation of inclusion bodies leading to progressive myoclonic epilepsy and neurodegeneration. Here we demonstrate that neuroserpin expression is regulated by thyroid hormone (T3). Neuroserpin RNA levels are down-regulated in cortical layers II/III and VIa, the hippocampu

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166 since deposited on 2008-02-11
Acq. date: 2025-11-08

Additional indexing

Creators (Authors)

  • Navarro-Yubero, C
    affiliation.icon.alt
  • Cuadrado, A
    affiliation.icon.alt
  • Sonderegger, P
    affiliation.icon.alt
  • Muñoz, A
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
123

Number

Number

Number
1-2

Page Range

Page Range

Page Range
56

Page end

Page end

Page end
65

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Thyroid hormone, Brain, Gene regulation, PC12 cells, RNA stability, Neuroserpin

Language

Language

Language
English

Publication date

Publication date

Publication date
2004-04-07

Date available

Date available

Date available
2008-02-11

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0169-328X

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Project Title

Project Title

Project Title
Fondo de Investigaciones Sanitarias, Ministerio de Sanidad y Consumo of Spain; Ministerio de Ciencia y Technololgía of Spain, Grant SAF2001-2291

Metrics

Views

166 since deposited on 2008-02-11
Acq. date: 2025-11-08

Citations

Citation copied

Navarro-Yubero, C., Cuadrado, A., Sonderegger, P., & Muñoz, A. (2004). Neuroserpin is post-transcriptionally regulated by thyroid hormone. Molecular Brain Research, 123(1–2), 56–65. https://doi.org/10.1016/j.molbrainres.2003.12.018

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