Publication: DIGESTIF: A universal quality standard for the control of bottom-up proteomics experiments
Date
Date
Date
2015
Journal Article
Published version
Abstract
Abstract
Abstract
In bottom-up mass spectrometry-based proteomics analyses, variability at any step of the process, particularly during sample proteolysis, directly affects the sensitivity, accuracy, and precision of peptide detection and quantification. Currently, no generic internal standards are available to control the quality of sample processing steps. This makes it difficult to assess the comparability of MS proteomic data obtained under different experimental conditions. Here, we describe the design, synthesis, and validation of a universal pro
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9 since deposited on 2015-01-16
Acq. date: 2025-11-12
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2 since deposited on 2015-01-16
Acq. date: 2025-11-12
Additional indexing
Creators (Authors)
- Lebert, Dorothée
- Louwagie, Mathilde
- Goetze, Sandra
- Picard, Guillaume
- Ossola, Reto
- Duquesne, Caroline
- Ferro, Myriam
- Rinner, Oliver
- Aebersold, Ruedi
- Garin, Jérôme
- Mouz, Nicolas
- Brunner, Erich
- Brun, Virginie
Volume
Volume
Volume
14
Number
Number
Number
2
Page range/Item number
Page range/Item number
Page range/Item number
787
Page end
Page end
Page end
803
Item Type
Item Type
Item Type
Journal Article
In collections
Language
Language
Language
English
Publication date
Publication date
Publication date
2015
Date available
Date available
Date available
2015-01-16
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1535-3893
Additional Information
Additional Information
Additional Information
This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Journal of proteome research], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [http://pubs.acs.org/doi/abs/10.1021/pr500834z].
OA Status
OA Status
OA Status
Green
Publisher DOI
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9 since deposited on 2015-01-16
Acq. date: 2025-11-12
Views
2 since deposited on 2015-01-16
Acq. date: 2025-11-12
Green Open Access
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