Publication: DIGESTIF: A universal quality standard for the control of bottom-up proteomics experiments
DIGESTIF: A universal quality standard for the control of bottom-up proteomics experiments
Date
Date
Date
Citations
Lebert, D., Louwagie, M., Goetze, S., Picard, G., Ossola, R., Duquesne, C., Basler, K., Ferro, M., Rinner, O., Aebersold, R., Garin, J., Mouz, N., Brunner, E., & Brun, V. (2015). DIGESTIF: A universal quality standard for the control of bottom-up proteomics experiments. Journal of Proteome Research, 14(2), 787–803. https://doi.org/10.1021/pr500834z
Abstract
Abstract
Abstract
In bottom-up mass spectrometry-based proteomics analyses, variability at any step of the process, particularly during sample proteolysis, directly affects the sensitivity, accuracy, and precision of peptide detection and quantification. Currently, no generic internal standards are available to control the quality of sample processing steps. This makes it difficult to assess the comparability of MS proteomic data obtained under different experimental conditions. Here, we describe the design, synthesis, and validation of a universal pro
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Lebert, Dorothée
- Louwagie, Mathilde
- Goetze, Sandra
- Picard, Guillaume
- Ossola, Reto
- Duquesne, Caroline
- Ferro, Myriam
- Rinner, Oliver
- Aebersold, Ruedi
- Garin, Jérôme
- Mouz, Nicolas
- Brunner, Erich
- Brun, Virginie
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
Additional Information
Additional Information
Additional Information
OA Status
OA Status
OA Status
Publisher DOI
Metrics
Downloads
Views
Citations
Lebert, D., Louwagie, M., Goetze, S., Picard, G., Ossola, R., Duquesne, C., Basler, K., Ferro, M., Rinner, O., Aebersold, R., Garin, J., Mouz, N., Brunner, E., & Brun, V. (2015). DIGESTIF: A universal quality standard for the control of bottom-up proteomics experiments. Journal of Proteome Research, 14(2), 787–803. https://doi.org/10.1021/pr500834z
