Publication: The Impact of Ca2+ on Intracellular Distribution of Hemoglobin in Human Erythrocytes
The Impact of Ca2+ on Intracellular Distribution of Hemoglobin in Human Erythrocytes
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Livshits, L., Peretz, S., Bogdanova, A., Zoabi, H., Eitam, H., Barshtein, G., Galindo, C., Feldman, Y., Pajić-Lijaković, I., Koren, A., Gassmann, M., & Levin, C. (2023). The Impact of Ca2+ on Intracellular Distribution of Hemoglobin in Human Erythrocytes. Cells, 12(18), 2280. https://doi.org/10.3390/cells12182280
Abstract
Abstract
Abstract
The membrane-bound hemoglobin (Hb) fraction impacts red blood cell (RBC) rheology and metabolism. Therefore, Hb–RBC membrane interactions are precisely controlled. For instance, the signaling function of membrane-bound deoxy-Hb and the structure of the docking sites in the cytosolic domain of the anion exchanger 1 (AE-1) protein are well documented; however, much less is known about the interaction of Hb variants with the erythrocyte’s membrane. Here, we identified factors other than O2 availability that control Hb abundance in the me
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Creators (Authors)
- Livshits, Leonid
- Peretz, Sari
- Bogdanova, Anna
- Zoabi, Hiba
- Eitam, Harel
- Barshtein, Gregory
- Galindo, Cindy
- Feldman, Yuri
- Pajić-Lijaković, Ivana
- Koren, Ariel
- Gassmann, Max
- Levin, Carina
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Citations
Livshits, L., Peretz, S., Bogdanova, A., Zoabi, H., Eitam, H., Barshtein, G., Galindo, C., Feldman, Y., Pajić-Lijaković, I., Koren, A., Gassmann, M., & Levin, C. (2023). The Impact of Ca2+ on Intracellular Distribution of Hemoglobin in Human Erythrocytes. Cells, 12(18), 2280. https://doi.org/10.3390/cells12182280
