Publication: Statement on in vitro protein digestibility tests in allergenicity and protein safety assessment of genetically modified plants
Statement on in vitro protein digestibility tests in allergenicity and protein safety assessment of genetically modified plants
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EFSA Panel on Genetically Modified Organisms (GMO), Naegeli, H., Bresson, J.-L., Dalmay, T., Dewhurst, I. C., Epstein, M. M., Firbank, L. G., Guerche, P., Hejatko, J., Moreno, F. J., Mullins, E., Nogué, F., Rostoks, N., Sánchez Serrano, J. J., Savoini, G., Veromann, E., Veronesi, F., & Dumont, A. F. (2021). Statement on in vitro protein digestibility tests in allergenicity and protein safety assessment of genetically modified plants. EFSA Journal, 19(1), e06350. https://doi.org/10.2903/j.efsa.2021.6350
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This statement supplements and updates the GMO Panel guidance document on allergenicity of genetically modified (GM) plants published in 2017. In that guidance document, the GMO Panel considered that additional investigations on in vitro protein digestibility were needed before providing any additional recommendations in the form of guidance to applicants. Thus, an interim phase was proposed to assess the utility of an enhanced in vitro digestion test, as compared to the classical pepsin resistance test. Historically, resistance to de
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EFSA Panel on Genetically Modified Organisms (GMO), Naegeli, H., Bresson, J.-L., Dalmay, T., Dewhurst, I. C., Epstein, M. M., Firbank, L. G., Guerche, P., Hejatko, J., Moreno, F. J., Mullins, E., Nogué, F., Rostoks, N., Sánchez Serrano, J. J., Savoini, G., Veromann, E., Veronesi, F., & Dumont, A. F. (2021). Statement on in vitro protein digestibility tests in allergenicity and protein safety assessment of genetically modified plants. EFSA Journal, 19(1), e06350. https://doi.org/10.2903/j.efsa.2021.6350
