Publication: Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele
Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele
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Daan, S., Spoelstra, K., Albrecht, U., Schmutz, I., Daan, M., Daan, B., Rienks, F., Poletaeva, I., Dell’Omo, G., Vyssotski, A., & Lipp, H. P. (2011). Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele. Journal of Biological Rhythms, 26(2), 118–129. https://doi.org/10.1177/0748730410397645
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Daily patterns of animal behavior are potentially of vast functional importance. Fitness benefits have been identified in nature by the association between individual timing and survival or by the fate of individuals after experimental deletion of their circadian pacemaker. The recent advances in unraveling the molecular basis of circadian timing enable new approaches to natural selection on timing. The investigators report on the effect and fate of the mutant Per2(Brdm1) allele in 4 replicate populations of house mice in a seminatura
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Daan, S., Spoelstra, K., Albrecht, U., Schmutz, I., Daan, M., Daan, B., Rienks, F., Poletaeva, I., Dell’Omo, G., Vyssotski, A., & Lipp, H. P. (2011). Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele. Journal of Biological Rhythms, 26(2), 118–129. https://doi.org/10.1177/0748730410397645