Publication: Healing kinetics of oral soft tissue wounds treated with recombinant epidermal growth factor: Translation from a canine model
Healing kinetics of oral soft tissue wounds treated with recombinant epidermal growth factor: Translation from a canine model
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Ben Amara, H., Thoma, D. S., Schwarz, F., Song, H. Y., Capetillo, J., & Koo, K.-T. (2019). Healing kinetics of oral soft tissue wounds treated with recombinant epidermal growth factor: Translation from a canine model. Journal of Clinical Periodontology, 46(1), 105–117. https://doi.org/10.1111/jcpe.13035
Abstract
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Abstract
OBJECTIVE To test whether or not topically administered recombinant human epidermal growth factor (rhEGF) accelerates the early healing phase of oral soft tissue wounds. METHODS One day following the creation of palatal defects (n = 6/animal), 14 dogs were allocated to one of the following five groups: spontaneous healing (SH), vehicle ointment (V), vehicle ointment + rhEGF at concentrations of 1 μg/g (EGF1), 10 μg/g (EGF10) or 50 μg/g (EGF50). Topical administration of ointments was repeated twice per day until sacrifice at days 8 an
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- Ben Amara, Heithem
- Thoma, Daniel S
- Schwarz, Frank
- Song, Hyun Young
- Capetillo, Joseph
- Koo, Ki-Tae
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Ben Amara, H., Thoma, D. S., Schwarz, F., Song, H. Y., Capetillo, J., & Koo, K.-T. (2019). Healing kinetics of oral soft tissue wounds treated with recombinant epidermal growth factor: Translation from a canine model. Journal of Clinical Periodontology, 46(1), 105–117. https://doi.org/10.1111/jcpe.13035
