Publication: Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin.
Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin.
Date
Date
Date
Citations
Dyshlovoy, S. A., Otte, K., Venz, S., Hauschild, J., Junker, H., Makarieva, T. N., Balabanov, S., Alsdorf, W. H., Madanchi, R., Honecker, F., Bokemeyer, C., Stonik, V. A., & von Amsberg, G. (2017). Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin. Proteomics, 17, 1700048. https://doi.org/10.1002/pmic.201700048
Abstract
Abstract
Abstract
Rhizochalinin (Rhiz) is a novel marine natural sphingolipid-like compound, which shows promising in vitro and in vivo activity in human castration-resistant prostate cancer. In the present study, a global proteome screening approach was applied to investigate molecular targets and biological processes affected by Rhiz in castration-resistant prostate cancer. Bioinformatical analysis of the data predicted an antimigratory effect of Rhiz on cancer cells. Validation of proteins involved in the cancer-associated processes, including cell
Additional indexing
Creators (Authors)
- Dyshlovoy, Sergey A
- Otte, Katharina
- Venz, Simone
- Hauschild, Jessica
- Junker, Heike
- Makarieva, Tatyana N
- Balabanov, Stefan
- Alsdorf, Winfried H
- Madanchi, Ramin
- Honecker, Friedemann
- Bokemeyer, Carsten
- Stonik, Valentin A
- von Amsberg, Gunhild
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Citations
Dyshlovoy, S. A., Otte, K., Venz, S., Hauschild, J., Junker, H., Makarieva, T. N., Balabanov, S., Alsdorf, W. H., Madanchi, R., Honecker, F., Bokemeyer, C., Stonik, V. A., & von Amsberg, G. (2017). Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin. Proteomics, 17, 1700048. https://doi.org/10.1002/pmic.201700048
