Publication: The Different Pathways of Epicardial Adipose Tissue across the Heart Failure Phenotypes: From Pathophysiology to Therapeutic Target
The Different Pathways of Epicardial Adipose Tissue across the Heart Failure Phenotypes: From Pathophysiology to Therapeutic Target
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Rossi, V. A., Gruebler, M., Monzo, L., Galluzzo, A., & Beltrami, M. (2023). The Different Pathways of Epicardial Adipose Tissue across the Heart Failure Phenotypes: From Pathophysiology to Therapeutic Target. International Journal of Molecular Sciences, 24(7), 6838. https://doi.org/10.3390/ijms24076838
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Epicardial adipose tissue (EAT) is an endocrine and paracrine organ constituted by a layer of adipose tissue directly located between the myocardium and visceral pericardium. Under physiological conditions, EAT exerts protective effects of brown-like fat characteristics, metabolizing excess fatty acids, and secreting anti-inflammatory and anti-fibrotic cytokines. In certain pathological conditions, EAT acquires a proatherogenic transcriptional profile resulting in increased synthesis of biologically active adipocytokines with proinfla
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- Rossi, Valentina A
- Gruebler, Martin
- Monzo, Luca
- Galluzzo, Alessandro
- Beltrami, Matteo
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Rossi, V. A., Gruebler, M., Monzo, L., Galluzzo, A., & Beltrami, M. (2023). The Different Pathways of Epicardial Adipose Tissue across the Heart Failure Phenotypes: From Pathophysiology to Therapeutic Target. International Journal of Molecular Sciences, 24(7), 6838. https://doi.org/10.3390/ijms24076838
