Publication: Angeborene Störungen des High-density-Lipoprotein-Stoffwechsels
Angeborene Störungen des High-density-Lipoprotein-Stoffwechsels
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von Eckardstein, A. (2019). Angeborene Störungen des High-density-Lipoprotein-Stoffwechsels. Der Internist, 60(12), 1311–1318. https://doi.org/10.1007/s00108-019-00700-3
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Both low and very high levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of atherosclerotic cardiovascular disease (ASCVD) and shorten life expectancy. Low and high levels of HDL‑C are often caused by underlying diseases, lifestyle or medication, which should primarily be excluded. Much less frequently, monogenic diseases due to mutations in the APOA1, ABCA1 and LCAT genes are the cause of very low or unmeasurable HDL‑C levels or in the CETP, LIPC and SCARB1 genes for very high HDL‑C values. Genetic and detailed
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von Eckardstein, A. (2019). Angeborene Störungen des High-density-Lipoprotein-Stoffwechsels. Der Internist, 60(12), 1311–1318. https://doi.org/10.1007/s00108-019-00700-3