Publication: Distinct functions of human RecQ helicases during DNA replication
Distinct functions of human RecQ helicases during DNA replication
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Urban, V., Dobrovolna, J., & Janscak, P. (2017). Distinct functions of human RecQ helicases during DNA replication. Biophysical Chemistry, 225, 20–26. https://doi.org/10.1016/j.bpc.2016.11.005
Abstract
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Abstract
DNA replication is the most vulnerable process of DNA metabolism in proliferating cells and therefore it is tightly controlled and coordinated with processes that maintain genomic stability. Human RecQ helicases are among the most important factors involved in the maintenance of replication fork integrity, especially under conditions of replication stress. RecQ helicases promote recovery of replication forks being stalled due to different replication roadblocks of either exogenous or endogenous source. They prevent generation of aberr
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- Urban, Vaclav
- Dobrovolna, Jana
- Janscak, Pavel
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Citations
Urban, V., Dobrovolna, J., & Janscak, P. (2017). Distinct functions of human RecQ helicases during DNA replication. Biophysical Chemistry, 225, 20–26. https://doi.org/10.1016/j.bpc.2016.11.005
