Publication: The mouse isolated perfused kidney technique
The mouse isolated perfused kidney technique
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Czogalla, J., Schweda, F., & Loffing, J. (2016). The mouse isolated perfused kidney technique. Journal of Visualized Experiments, 117, e54712. https://doi.org/10.3791/54712
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The mouse isolated perfused kidney (MIPK) is a technique for keeping a mouse kidney under ex vivo conditions perfused and functional for 1 hr. This is a prerequisite for studying the physiology of the isolated organ and for many innovative applications that may be possible in the future, including perfusion decellularization for kidney bioengineering or the administration of anti-rejection or genome-editing drugs in high doses to prime the kidney for transplantation. During the time of the perfusion, the kidney can be manipulated, ren
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Czogalla, J., Schweda, F., & Loffing, J. (2016). The mouse isolated perfused kidney technique. Journal of Visualized Experiments, 117, e54712. https://doi.org/10.3791/54712