Tolerability, assessment, and prediction of psilocybin-induced altered states of consciousness

Abstract

Since the early 1990s, hallucinogenic drugs, such as psilocybin, have been increasingly used to investigate the neuronal basis of altered states of consciousness and psychosis. Furthermore, renewed interest has emerged in using these drugs as an adjunct to psychotherapy. Nevertheless, the therapeutic and experimental use of these substances is still controversial due to fears of potential harm. Although the experience of many investigators suggests that potential risks are minimal when these drugs are administered in a carefully monit Show more