Publication: Grover’s-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy
Grover’s-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy
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Koelzer, V. H., Buser, T., Willi, N., Rothschild, S. I., Wicki, A., Schiller, P., Cathomas, G., Zippelius, A., & Mertz, K. D. (2016). Grover’s-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy. Journal for ImmunoTherapy of Cancer, 4, 47. https://doi.org/10.1186/s40425-016-0151-z
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BACKGROUND: Dermatologic toxicity is an important adverse effect of immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death 1 receptor (PD-1) or PD ligand 1 (PD-L1). Skin toxicity most commonly includes a maculopapular erythematous rash and pruritus. Rarely life threatening complications such as Steven's Johnson syndrome or toxic epidermal necrolysis may occur. CASE PRESENTATION: Here we report the uncommon event of a drug-induced transient acantholytic dermatosis (Grover's
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Koelzer, V. H., Buser, T., Willi, N., Rothschild, S. I., Wicki, A., Schiller, P., Cathomas, G., Zippelius, A., & Mertz, K. D. (2016). Grover’s-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy. Journal for ImmunoTherapy of Cancer, 4, 47. https://doi.org/10.1186/s40425-016-0151-z