Publication: Multicentric performance analysis of HCV quantification assays and its potential relevance for HCV treatment
Multicentric performance analysis of HCV quantification assays and its potential relevance for HCV treatment
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Wiesmann, F., Naeth, G., Berger, A., Hirsch, H. H., Regenass, S., Ross, R. S., Sarrazin, C., Wedemeyer, H., Knechten, H., & Braun, P. (2016). Multicentric performance analysis of HCV quantification assays and its potential relevance for HCV treatment. Medical Microbiology and Immunology, 205(3), 263–268. https://doi.org/10.1007/s00430-015-0443-9
Abstract
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Abstract
An accurate quantification of low viremic HCV RNA plasma samples has gained importance since the approval of direct acting antivirals and since only one single measurement predicts the necessity of a prolonged or shortened therapy. As reported previously, HCV quantification assays such as Abbott RealTime HCV and Roche COBAS AmpliPrep/COBAS TaqMan HCV version 2 (CTM v2) may vary in sensitivity and precision particularly in low-level viremia. Importantly, substantial variations were previously demonstrated between some of these assays c
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Creators (Authors)
- Wiesmann, F
- Naeth, G
- Berger, A
- Hirsch, H H
- Regenass, S
- Ross, R S
- Sarrazin, C
- Wedemeyer, H
- Knechten, H
- Braun, P
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Citations
Wiesmann, F., Naeth, G., Berger, A., Hirsch, H. H., Regenass, S., Ross, R. S., Sarrazin, C., Wedemeyer, H., Knechten, H., & Braun, P. (2016). Multicentric performance analysis of HCV quantification assays and its potential relevance for HCV treatment. Medical Microbiology and Immunology, 205(3), 263–268. https://doi.org/10.1007/s00430-015-0443-9
