Publication: Dynamics of Bacteriorhodopsin in the Dark‐Adapted State from Solution NMR
Dynamics of Bacteriorhodopsin in the Dark‐Adapted State from Solution NMR
Date
Date
Date
Citations
Kooijman, L., Schuster, M., Baumann, C., Jurt, S., Löhr, F., Fürtig, B., Güntert, P., & Zerbe, O. (2020). Dynamics of Bacteriorhodopsin in the Dark‐Adapted State from Solution NMR. Angewandte Chemie Internationale Edition, anie.202004393. https://doi.org/10.1002/anie.202004393
Abstract
Abstract
Abstract
To achieve efficient proton pumping in the light-driven proton pump bacteriorhodopsin, the protein must be tightly coupled to the retinal to rapidly convert retinal isomerization into protein structural rearrangements. Methyl group dynamics of bR embedded in lipid nanodiscs were determined in the dark-adapted state, and were found to be mostly well-ordered at the cytosolic side. Methyl groups in the M145A mutant of bR, which displays only 10% residual proton pumping activity, are less well ordered suggesting a link between side chain
Additional indexing
Creators (Authors)
- Kooijman, Laurens
- Schuster, Matthias
- Baumann, Christian
- Jurt, Simon
- Löhr, Frank
- Fürtig, Boris
- Güntert, Peter
Journal/Series Title
Journal/Series Title
Journal/Series Title
Page Range
Page Range
Page Range
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Funder name
Funder name
Funder name
Forschungskredit der Universität Zürich
Grant ID
Grant ID
Grant ID
FK- 18-083
Project Title
Project Title
Project Title
Citations
Kooijman, L., Schuster, M., Baumann, C., Jurt, S., Löhr, F., Fürtig, B., Güntert, P., & Zerbe, O. (2020). Dynamics of Bacteriorhodopsin in the Dark‐Adapted State from Solution NMR. Angewandte Chemie Internationale Edition, anie.202004393. https://doi.org/10.1002/anie.202004393
