Publication: Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model
Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model
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Hetze, S., Barthel, L., Lückemann, L., Günther, H. S., Wülfing, C., Salem, Y., Jakobs, M., Hörbelt-Grünheidt, T., Petschulat, J., Bendix, I., Weber-Stadlbauer, U., Sure, U., Schedlowski, M., & Hadamitzky, M. (2022). Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model. Brain, Behavior, and Immunity, 106, 270–279. https://doi.org/10.1016/j.bbi.2022.09.006
Abstract
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Abstract
Mechanistic target of rapamycin (mTOR)-signaling is one key driver of glioblastoma (GBM), facilitating tumor growth by promoting the shift to an anti-inflammatory, pro-cancerogenic microenvironment. Even though mTOR inhibitors such as rapamycin (RAPA) have been shown to interfere with GBM disease progression, frequently chaperoned toxic drug side effects urge the need for developing alternative or supportive treatment strategies. Importantly, previous work document that taste-immune associative learning with RAPA may be utilized to in
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Creators (Authors)
- Hetze, Susann
- Barthel, Lennart
- Lückemann, Laura
- Günther, Hauke S
- Wülfing, Clemens
- Salem, Yasmin
- Jakobs, Marie
- Hörbelt-Grünheidt, Tina
- Petschulat, Jasmin
- Bendix, Ivo
- Weber-Stadlbauer, Ulrike
- Sure, Ulrich
- Schedlowski, Manfred
- Hadamitzky, Martin
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Citations
Hetze, S., Barthel, L., Lückemann, L., Günther, H. S., Wülfing, C., Salem, Y., Jakobs, M., Hörbelt-Grünheidt, T., Petschulat, J., Bendix, I., Weber-Stadlbauer, U., Sure, U., Schedlowski, M., & Hadamitzky, M. (2022). Taste-immune associative learning amplifies immunopharmacological effects and attenuates disease progression in a rat glioblastoma model. Brain, Behavior, and Immunity, 106, 270–279. https://doi.org/10.1016/j.bbi.2022.09.006
