Publication: Performance of three freely available methods for extracting white matter hyperintensities: FreeSurfer, UBO Detector, and BIANCA
Performance of three freely available methods for extracting white matter hyperintensities: FreeSurfer, UBO Detector, and BIANCA
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Hotz, I., Deschwanden, P. F., Liem, F., Mérillat, S., Malagurski, B., Kollias, S., & Jäncke, L. (2022). Performance of three freely available methods for extracting white matter hyperintensities: FreeSurfer, UBO Detector, and BIANCA. Human Brain Mapping, 43(5), 1481–1500. https://doi.org/10.1002/hbm.25739
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White matter hyperintensities (WMH) of presumed vascular origin are frequently found in MRIs of healthy older adults. WMH are also associated with aging and cognitive decline. Here, we compared and validated three algorithms for WMH extraction: FreeSurfer (T1w), UBO Detector (T1w + FLAIR), and FSL's Brain Intensity AbNormality Classification Algorithm (BIANCA; T1w + FLAIR) using a longitudinal dataset comprising MRI data of cognitively healthy older adults (baseline N = 231, age range 64-87 years). As reference we manually segmented W
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Hotz, I., Deschwanden, P. F., Liem, F., Mérillat, S., Malagurski, B., Kollias, S., & Jäncke, L. (2022). Performance of three freely available methods for extracting white matter hyperintensities: FreeSurfer, UBO Detector, and BIANCA. Human Brain Mapping, 43(5), 1481–1500. https://doi.org/10.1002/hbm.25739
