Publication: A Three-Dimensional $\textit{Ex Vivo}$ Model for Investigating Disease Dynamics and Therapeutic Strategies in Childhood Acute Lymphoblastic Leukemia
A Three-Dimensional $\textit{Ex Vivo}$ Model for Investigating Disease Dynamics and Therapeutic Strategies in Childhood Acute Lymphoblastic Leukemia
Date
Date
Date
Citations
Kanari, M. (2025). A Three-Dimensional $\textit{Ex Vivo}$ Model for Investigating Disease Dynamics and Therapeutic Strategies in Childhood Acute Lymphoblastic Leukemia. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-277718
Abstract
Abstract
Abstract
Acute lymphoblastic leukemia (ALL) is the most prevalent pediatric malignancy, characterized by the uncontrollable proliferation of immature lymphocytes in the bone marrow (BM). Advances in treatment regimens have increased the overall survival of ALL patients significantly; however, approximately 20% of the cases exhibit resistance to treatment and relapse. The underlying molecular mechanisms of refractory or relapsed leukemia are yet elusive, but the protective role of the BM niche has widely been established. The microenvironment t
Metrics
Downloads
Views
Citations
Additional indexing
Creators (Authors)
Faculty
Faculty
Faculty
Item Type
Item Type
Item Type
Referees
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Place of Publication
Place of Publication
Place of Publication
Publication date
Publication date
Publication date
Date available
Date available
Date available
Number of pages
Number of pages
Number of pages
OA Status
OA Status
OA Status
Metrics
Downloads
Views
Citations
Citations
Kanari, M. (2025). A Three-Dimensional $\textit{Ex Vivo}$ Model for Investigating Disease Dynamics and Therapeutic Strategies in Childhood Acute Lymphoblastic Leukemia. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-277718
