Publication: Effect of Monthly High-Dose Vitamin D on Mental Health in Older Adults: Secondary Analysis of a RCT
Effect of Monthly High-Dose Vitamin D on Mental Health in Older Adults: Secondary Analysis of a RCT
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Gugger, A., Marzel, A., Orav, E. J., Willett, W. C., Dawson-Hughes, B., Theiler, R., Freystätter, G., Egli, A., & Bischoff-Ferrari, H. A. (2019). Effect of Monthly High-Dose Vitamin D on Mental Health in Older Adults: Secondary Analysis of a RCT. Journal of the American Geriatrics Society, 67, 1211–1217. https://doi.org/10.1111/jgs.15808
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OBJECTIVES: To test the effect of monthly high-dose vitamin D supplementation on mental health in pre-frail older adults. DESIGN: Ancillary study of a 1-year double-blind randomized clinical trial conducted in Zurich, Switzerland. SETTING AND PARTICIPANTS: A total of 200 community-dwelling adults 70 years and older with a prior fall event in the last year. Participants were randomized to receive 24 000 IU vitamin D3 (considered standard of care), 60 000 IU vitamin D3 , or 24 000 IU vitamin D3 plus 300 μg calcifediol per month. MEASURE
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Gugger, A., Marzel, A., Orav, E. J., Willett, W. C., Dawson-Hughes, B., Theiler, R., Freystätter, G., Egli, A., & Bischoff-Ferrari, H. A. (2019). Effect of Monthly High-Dose Vitamin D on Mental Health in Older Adults: Secondary Analysis of a RCT. Journal of the American Geriatrics Society, 67, 1211–1217. https://doi.org/10.1111/jgs.15808