Publication: Blue light-induced retinal lesions, intraretinal vascular leakage and edema formation in the all-cone mouse retina
Blue light-induced retinal lesions, intraretinal vascular leakage and edema formation in the all-cone mouse retina
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Geiger, P., Barben, M., Grimm, C., & Samardzija, M. (2015). Blue light-induced retinal lesions, intraretinal vascular leakage and edema formation in the all-cone mouse retina. Cell Death and Disease, 6, e1985. https://doi.org/10.1038/cddis.2015.333
Abstract
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Abstract
Little is known about the mechanisms underlying macular degenerations, mainly for the scarcity of adequate experimental models to investigate cone cell death. Recently, we generated R91W;Nrl(-/-) double-mutant mice, which display a well-ordered all-cone retina with normal retinal vasculature and a strong photopic function that generates useful vision. Here we exposed R91W;Nrl(-/-) and wild-type (wt) mice to toxic levels of blue light and analyzed their retinas at different time points post illumination (up to 10 days). While exposure
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- Geiger, P
- Barben, M
- Grimm, C
- Samardzija, M
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Geiger, P., Barben, M., Grimm, C., & Samardzija, M. (2015). Blue light-induced retinal lesions, intraretinal vascular leakage and edema formation in the all-cone mouse retina. Cell Death and Disease, 6, e1985. https://doi.org/10.1038/cddis.2015.333
