Publication:

An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety

Date

Date

Date
2021
Journal Article
Published version

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Heringlake, M., Alvarez, J., Bettex, D., Bouchez, S., Fruhwald, S., Girardis, M., Grossini, E., Guarracino, F., Herpain, A., Toller, W., Tritapepe, L., & Pollesello, P. (2021). An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety. Expert Review of Cardiovascular Therapy, 19(4), 325–335. https://doi.org/10.1080/14779072.2021.1905520

Abstract

Abstract

Abstract

Introduction: In the 20 years since its introduction to the palette of intravenous hemodynamic therapies, the inodilator levosimendan has established itself as a valuable asset for the management of acute decompensated heart failure. Its pharmacology is notable for delivering inotropy via calcium sensitization without an increase in myocardial oxygen consumption.Areas covered: Experience with levosimendan has led to its applications expanding into perioperative hemodynamic support and various critical care settings, as well as an arra

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41 since deposited on 2021-11-10
Acq. date: 2025-11-12

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Creators (Authors)

  • Heringlake, Matthias
    affiliation.icon.alt
  • Alvarez, Julian
    affiliation.icon.alt
  • Bettex, Dominique
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  • Bouchez, Stefaan
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  • Fruhwald, Sonja
    affiliation.icon.alt
  • Girardis, Massimo
    affiliation.icon.alt
  • Grossini, Elena
    affiliation.icon.alt
  • Guarracino, Fabio
    affiliation.icon.alt
  • Herpain, Antoine
    affiliation.icon.alt
  • Toller, Wolfgang
    affiliation.icon.alt
  • Tritapepe, Luigi
    affiliation.icon.alt
  • Pollesello, Piero
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
19

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
325

Page end

Page end

Page end
335

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
German

Publication date

Publication date

Publication date
2021-04

Date available

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Date available
2021-11-10

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1477-9072

OA Status

OA Status

OA Status
Closed

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PubMed ID

PubMed ID

Metrics

Views

41 since deposited on 2021-11-10
Acq. date: 2025-11-12

Citations

Citation copied

Heringlake, M., Alvarez, J., Bettex, D., Bouchez, S., Fruhwald, S., Girardis, M., Grossini, E., Guarracino, F., Herpain, A., Toller, W., Tritapepe, L., & Pollesello, P. (2021). An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety. Expert Review of Cardiovascular Therapy, 19(4), 325–335. https://doi.org/10.1080/14779072.2021.1905520

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