Publication: Anti-IgLON5 Disease: A New Bulbar-Onset Motor Neuron Mimic Syndrome
Anti-IgLON5 Disease: A New Bulbar-Onset Motor Neuron Mimic Syndrome
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Werner, J., Jelcic, I., Schwarz, E. I., Probst-Müller, E., Nilsson, J., Schwizer, B., Bloch, K. E., Lutterotti, A., Jung, H.-H., & Schreiner, B. (2021). Anti-IgLON5 Disease: A New Bulbar-Onset Motor Neuron Mimic Syndrome. Neurology: Neuroimmunology and Neuroinflammation, 8, e962. https://doi.org/10.1212/NXI.0000000000000962
Abstract
Abstract
Abstract
OBJECTIVE: To expand the spectrum of anti-IgLON5 disease by adding 5 novel anti-IgLON5-seropositive cases with bulbar motor neuron disease-like phenotype. METHODS: We characterized the clinical course, brain MRI and laboratory findings, and therapy response in these 5 patients. RESULTS: Patients were severely affected by bulbar impairment and its respiratory consequences. Sleep-related breathing disorders and parasomnias were common. All patients showed clinical or electrophysiologic signs of motor neuron disease without fulfilling th
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Creators (Authors)
- Werner, Jana
- Jelcic, Ilijas
- Schwarz, Esther Irene
- Probst-Müller, Elisabeth
- Nilsson, Jakob
- Schwizer, Bernhard
- Bloch, Konrad Ernst
- Lutterotti, Andreas
- Jung, Hans-Heinrich
- Schreiner, Bettina
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Citations
Werner, J., Jelcic, I., Schwarz, E. I., Probst-Müller, E., Nilsson, J., Schwizer, B., Bloch, K. E., Lutterotti, A., Jung, H.-H., & Schreiner, B. (2021). Anti-IgLON5 Disease: A New Bulbar-Onset Motor Neuron Mimic Syndrome. Neurology: Neuroimmunology and Neuroinflammation, 8, e962. https://doi.org/10.1212/NXI.0000000000000962
