Publication: Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity.
Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity.
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Halfar, K., Rommel, C., Stocker, H., & Hafen, E. (2001). Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development, 128(9), 1687–1696.
Abstract
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Abstract
Ras mediates a plethora of cellular functions during development. In the developing eye of Drosophila, Ras performs three temporally separate functions. In dividing cells, it is required for growth but is not essential for cell cycle progression. In postmitotic cells, it promotes survival and subsequent differentiation of ommatidial cells. In the present paper, we have analyzed the different roles of Ras during eye development by using molecularly defined complete and partial loss-of-function mutations of Ras. We show that the three d
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- Halfar, K
- Rommel, C
- Stocker, H
- Hafen, E
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Halfar, K., Rommel, C., Stocker, H., & Hafen, E. (2001). Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development, 128(9), 1687–1696.
